The impact of subthalamic deep brain stimulation on caregivers of Parkinson's disease patients: an exploratory study.
Identifieur interne : 000500 ( Main/Exploration ); précédent : 000499; suivant : 000501The impact of subthalamic deep brain stimulation on caregivers of Parkinson's disease patients: an exploratory study.
Auteurs : Catharine J. Lewis [Allemagne] ; Franziska Maier ; Nina Horstkötter ; Carsten Eggers ; Veerle Visser-Vandewalle ; Elena Moro ; Mateusz Zurowski ; Jens Kuhn ; Christiane Woopen ; Lars TimmermannSource :
- Journal of neurology [ 1432-1459 ] ; 2015.
English descriptors
- KwdEn :
- MESH :
- physiology : Subthalamic Nucleus.
- psychology : Caregivers.
- therapy : Parkinson Disease.
- Deep Brain Stimulation, Female, Humans, Male, Middle Aged, Prospective Studies, Quality of Life.
Abstract
To study the caregivers' perception of their own well-being 1 year after subthalamic deep brain stimulation (STN-DBS) surgery in Parkinson's disease (PD) patients, using a qualitative and quantitative approach. 25 patients and caregivers, living together in partnerships, were examined before and at 3-month and 1-year follow-up (FU) after STN-DBS surgery. Semi-structured FU interviews concerning caregivers' own well-being under STN-DBS were conducted and analyzed: caregivers were accordingly assigned to positive or negative outcome groups. Quality of life (QoL), depression, apathy and anxiety of caregivers and patients were measured. These quantitative data were compared to the 1-year FU interview outcomes. Multiple comparisons analyzed caregiver group assignments based on these measurements. Logistic regression was used to find predictors. Additionally, patients' mood ratings were used in multiple comparisons with caregivers' subjective outcome, to analyze the interaction of patient and caregiver ratings. At 3-month FU, caregivers were more indecisive concerning their own well-being than at 1-year FU. At 1-year FU, caregivers from the negative group had greater depression, anxiety and lower QoL ratings. They were significantly older compared to the positive group. Patients' depression showed significantly stronger improvement in the positive outcome group. Patients' apathy and depression ratings were significant covariates of caregivers' QoL. Our results show that at 1-year FU over 50 % of the caregivers rated their subjective well-being as negative. Especially older and more depressed caregivers are at risk. These caregivers and their partners should be monitored more closely to identify possible problems and help them adapt following surgery.
DOI: 10.1007/s00415-014-7571-9
PubMed: 25381461
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 000577
- to stream PubMed, to step Curation: 000577
- to stream PubMed, to step Checkpoint: 000577
- to stream Ncbi, to step Merge: 001957
- to stream Ncbi, to step Curation: 001957
- to stream Ncbi, to step Checkpoint: 001957
- to stream Main, to step Merge: 000501
- to stream Main, to step Curation: 000500
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The impact of subthalamic deep brain stimulation on caregivers of Parkinson's disease patients: an exploratory study.</title><author><name sortKey="Lewis, Catharine J" sort="Lewis, Catharine J" uniqKey="Lewis C" first="Catharine J" last="Lewis">Catharine J. Lewis</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, University Hospital Cologne, Kerpener Str. 62, 50937, Cologne, Germany, catharine.lewis@uk-koeln.de.</nlm:affiliation><country wicri:rule="url">Allemagne</country><wicri:regionArea>Department of Neurology, University Hospital Cologne, Kerpener Str. 62, 50937, Cologne, Germany</wicri:regionArea><wicri:noRegion>Germany</wicri:noRegion><wicri:noRegion>Germany</wicri:noRegion><wicri:noRegion>Germany</wicri:noRegion></affiliation></author><author><name sortKey="Maier, Franziska" sort="Maier, Franziska" uniqKey="Maier F" first="Franziska" last="Maier">Franziska Maier</name></author><author><name sortKey="Horstkotter, Nina" sort="Horstkotter, Nina" uniqKey="Horstkotter N" first="Nina" last="Horstkötter">Nina Horstkötter</name></author><author><name sortKey="Eggers, Carsten" sort="Eggers, Carsten" uniqKey="Eggers C" first="Carsten" last="Eggers">Carsten Eggers</name></author><author><name sortKey="Visser Vandewalle, Veerle" sort="Visser Vandewalle, Veerle" uniqKey="Visser Vandewalle V" first="Veerle" last="Visser-Vandewalle">Veerle Visser-Vandewalle</name></author><author><name sortKey="Moro, Elena" sort="Moro, Elena" uniqKey="Moro E" first="Elena" last="Moro">Elena Moro</name></author><author><name sortKey="Zurowski, Mateusz" sort="Zurowski, Mateusz" uniqKey="Zurowski M" first="Mateusz" last="Zurowski">Mateusz Zurowski</name></author><author><name sortKey="Kuhn, Jens" sort="Kuhn, Jens" uniqKey="Kuhn J" first="Jens" last="Kuhn">Jens Kuhn</name></author><author><name sortKey="Woopen, Christiane" sort="Woopen, Christiane" uniqKey="Woopen C" first="Christiane" last="Woopen">Christiane Woopen</name></author><author><name sortKey="Timmermann, Lars" sort="Timmermann, Lars" uniqKey="Timmermann L" first="Lars" last="Timmermann">Lars Timmermann</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2015">2015</date><idno type="RBID">pubmed:25381461</idno><idno type="pmid">25381461</idno><idno type="doi">10.1007/s00415-014-7571-9</idno><idno type="wicri:Area/PubMed/Corpus">000577</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000577</idno><idno type="wicri:Area/PubMed/Curation">000577</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000577</idno><idno type="wicri:Area/PubMed/Checkpoint">000577</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000577</idno><idno type="wicri:Area/Ncbi/Merge">001957</idno><idno type="wicri:Area/Ncbi/Curation">001957</idno><idno type="wicri:Area/Ncbi/Checkpoint">001957</idno><idno type="wicri:Area/Main/Merge">000501</idno><idno type="wicri:Area/Main/Curation">000500</idno><idno type="wicri:Area/Main/Exploration">000500</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">The impact of subthalamic deep brain stimulation on caregivers of Parkinson's disease patients: an exploratory study.</title><author><name sortKey="Lewis, Catharine J" sort="Lewis, Catharine J" uniqKey="Lewis C" first="Catharine J" last="Lewis">Catharine J. Lewis</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, University Hospital Cologne, Kerpener Str. 62, 50937, Cologne, Germany, catharine.lewis@uk-koeln.de.</nlm:affiliation><country wicri:rule="url">Allemagne</country><wicri:regionArea>Department of Neurology, University Hospital Cologne, Kerpener Str. 62, 50937, Cologne, Germany</wicri:regionArea><wicri:noRegion>Germany</wicri:noRegion><wicri:noRegion>Germany</wicri:noRegion><wicri:noRegion>Germany</wicri:noRegion></affiliation></author><author><name sortKey="Maier, Franziska" sort="Maier, Franziska" uniqKey="Maier F" first="Franziska" last="Maier">Franziska Maier</name></author><author><name sortKey="Horstkotter, Nina" sort="Horstkotter, Nina" uniqKey="Horstkotter N" first="Nina" last="Horstkötter">Nina Horstkötter</name></author><author><name sortKey="Eggers, Carsten" sort="Eggers, Carsten" uniqKey="Eggers C" first="Carsten" last="Eggers">Carsten Eggers</name></author><author><name sortKey="Visser Vandewalle, Veerle" sort="Visser Vandewalle, Veerle" uniqKey="Visser Vandewalle V" first="Veerle" last="Visser-Vandewalle">Veerle Visser-Vandewalle</name></author><author><name sortKey="Moro, Elena" sort="Moro, Elena" uniqKey="Moro E" first="Elena" last="Moro">Elena Moro</name></author><author><name sortKey="Zurowski, Mateusz" sort="Zurowski, Mateusz" uniqKey="Zurowski M" first="Mateusz" last="Zurowski">Mateusz Zurowski</name></author><author><name sortKey="Kuhn, Jens" sort="Kuhn, Jens" uniqKey="Kuhn J" first="Jens" last="Kuhn">Jens Kuhn</name></author><author><name sortKey="Woopen, Christiane" sort="Woopen, Christiane" uniqKey="Woopen C" first="Christiane" last="Woopen">Christiane Woopen</name></author><author><name sortKey="Timmermann, Lars" sort="Timmermann, Lars" uniqKey="Timmermann L" first="Lars" last="Timmermann">Lars Timmermann</name></author></analytic><series><title level="j">Journal of neurology</title><idno type="eISSN">1432-1459</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Caregivers (psychology)</term><term>Deep Brain Stimulation</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Parkinson Disease (therapy)</term><term>Prospective Studies</term><term>Quality of Life</term><term>Subthalamic Nucleus (physiology)</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Subthalamic Nucleus</term></keywords><keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Caregivers</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Deep Brain Stimulation</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Prospective Studies</term><term>Quality of Life</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To study the caregivers' perception of their own well-being 1 year after subthalamic deep brain stimulation (STN-DBS) surgery in Parkinson's disease (PD) patients, using a qualitative and quantitative approach. 25 patients and caregivers, living together in partnerships, were examined before and at 3-month and 1-year follow-up (FU) after STN-DBS surgery. Semi-structured FU interviews concerning caregivers' own well-being under STN-DBS were conducted and analyzed: caregivers were accordingly assigned to positive or negative outcome groups. Quality of life (QoL), depression, apathy and anxiety of caregivers and patients were measured. These quantitative data were compared to the 1-year FU interview outcomes. Multiple comparisons analyzed caregiver group assignments based on these measurements. Logistic regression was used to find predictors. Additionally, patients' mood ratings were used in multiple comparisons with caregivers' subjective outcome, to analyze the interaction of patient and caregiver ratings. At 3-month FU, caregivers were more indecisive concerning their own well-being than at 1-year FU. At 1-year FU, caregivers from the negative group had greater depression, anxiety and lower QoL ratings. They were significantly older compared to the positive group. Patients' depression showed significantly stronger improvement in the positive outcome group. Patients' apathy and depression ratings were significant covariates of caregivers' QoL. Our results show that at 1-year FU over 50 % of the caregivers rated their subjective well-being as negative. Especially older and more depressed caregivers are at risk. These caregivers and their partners should be monitored more closely to identify possible problems and help them adapt following surgery.</div></front></TEI><affiliations><list><country><li>Allemagne</li></country></list><tree><noCountry><name sortKey="Eggers, Carsten" sort="Eggers, Carsten" uniqKey="Eggers C" first="Carsten" last="Eggers">Carsten Eggers</name><name sortKey="Horstkotter, Nina" sort="Horstkotter, Nina" uniqKey="Horstkotter N" first="Nina" last="Horstkötter">Nina Horstkötter</name><name sortKey="Kuhn, Jens" sort="Kuhn, Jens" uniqKey="Kuhn J" first="Jens" last="Kuhn">Jens Kuhn</name><name sortKey="Maier, Franziska" sort="Maier, Franziska" uniqKey="Maier F" first="Franziska" last="Maier">Franziska Maier</name><name sortKey="Moro, Elena" sort="Moro, Elena" uniqKey="Moro E" first="Elena" last="Moro">Elena Moro</name><name sortKey="Timmermann, Lars" sort="Timmermann, Lars" uniqKey="Timmermann L" first="Lars" last="Timmermann">Lars Timmermann</name><name sortKey="Visser Vandewalle, Veerle" sort="Visser Vandewalle, Veerle" uniqKey="Visser Vandewalle V" first="Veerle" last="Visser-Vandewalle">Veerle Visser-Vandewalle</name><name sortKey="Woopen, Christiane" sort="Woopen, Christiane" uniqKey="Woopen C" first="Christiane" last="Woopen">Christiane Woopen</name><name sortKey="Zurowski, Mateusz" sort="Zurowski, Mateusz" uniqKey="Zurowski M" first="Mateusz" last="Zurowski">Mateusz Zurowski</name></noCountry><country name="Allemagne"><noRegion><name sortKey="Lewis, Catharine J" sort="Lewis, Catharine J" uniqKey="Lewis C" first="Catharine J" last="Lewis">Catharine J. Lewis</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Canada/explor/ParkinsonCanadaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000500 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000500 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Canada
|area= ParkinsonCanadaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:25381461
|texte= The impact of subthalamic deep brain stimulation on caregivers of Parkinson's disease patients: an exploratory study.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:25381461" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a ParkinsonCanadaV1
| This area was generated with Dilib version V0.6.29. |  |